The Role of the Glutathione Recycling System in Leaky Gut Syndrome
Glutathione is the main antioxidant that protects cellular mitochondria. Glutathione exists in reduced (GSH) and oxidized (GSSG) states. GSH (reduced glutathione) becomes GSSG (oxidized glutathione) by an enzyme called glutathione peroxidase. GSH can be regenerated from GSSG by the enzyme glutathione reductase. AS LONG AS these enzymes are working efficiently, your body is able to maintain this glutathione recycling system and you are fine. When this enzyme system fails, you get activation of iNOS and autoimmunity. The ability to activate these enzymes is critical for autoimmunity.
This says it all, GSH replenishing is essential in leaky gut, GSH-I is the most efficient method of replenishing GSH. Contact me, have a wonderful wkend